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CYTUVA

Analysis of blood oxygen saturation and heart frequency for sleep apnoea-hypopnoea syndrome (SAHS) diagnosis

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Contact Information

Basic Information

  • UniversityUniversidad de Valladolid
  • Center
  • DepartmentSignal Theory and Communications and Telematics Engineering
  • Investigation GroupBiomedical Engineering Group (GIB)


Description

Analysis of blood oxygen saturation and heart frequency for sleep apnoea-hypopnoea syndrome (SAHS) diagnosis. Polysomnography is the main source of information for sleep study. Automatic analysis of cardio-respiratory night signs is very useful for disease diagnosis, such as apnoea-hypopnoea syndrome diagnose (SAHS) or chronic obstructive pulmonary disease (COPD). The University of Valladolid’s group of biomedical informatics (GIB in its Spanish acronym) has developed some diagnosis methods through spectral, non-lineal analysis and time-frequency of polysomnographic registers. Development of predictive models based on machine learning. The main goal of these work lines is to develop and validate an e-Health tool within a new protocol of patient screening to significantly reduce the number of PSGs (night polysomnography). The screening test is based on the automatic analysis of blood oxygen saturation (SpO2) registered at the patient’s home. SpO2 can be easily obtained with a finger pulse oximeter. There are portable pulse oximeters which make this home test easier. The methodology is divided into 2 complementary phases: (i) screening of true negatives and (ii) screening of true positives. An expert system based on machine learning will be optimized in each phase in order to detect (i) subjects not suffering from SAHS without there being false negatives and (ii) patients suffering from SAHS without there being false positives. In order to maximize the diagnostic potential of the SpO2 signal, there will be 3 phases of automatic processing: (i) Feature extraction in order to obtain as much useful information as possible, (ii) feature selection in order to determine the optimal subset including relevant and non-redundant information, and (iii) pattern identification through machine learning algorithms. In order to provide this service to Special Care consultations, it is suggested the development of a comprehensive screening tool which uses cloud computing to analyse every SpO2 register. The results will be provided to the specialist in different formats: phone device and web. The user application will automatically manage the register transfer and the result display.


Other information

Number of researchers:

20

Development status:

Developed but not marketed

Intellectual Property Rights:

Patent

Differentiation in the market:

Simplificación Prueba. Adecuación al escenario real

Applicability of technology:

Yes

Companies and markets:

Public health and medical care services. Diagnostic solution, biomedical signal analysis.

Advantages:

Is is expected that a much more favorable cost-efficiency balance than the current SAHS diagnosis protocol is achieved, thus reducing costs and waiting lists, as well as optimizing the offered service. The trial setting is the patient’s home. Since it is carried out in appropriate environment conditions, the result will reflect the patient’s reality. The software developed for blood oxygen saturation signal analysis is 92% accurate.

Additional Information:

RETOS COLABORACIÓN (collaboration challenge) project. Funded by the Spanish Ministry of Economy and Finance and co-funded by the EU under the ERDF within the thematic objective “strengthening research, technological development and innovation”. Consortium formed by: OXIGEN Salud, Five Flames Mobile, the Biomedical Ingeneering Group (GIB in its Spanish acronym) and Rio Hortega University Hospital in Valladolid. ScreenOX project.

UNESCO Code:

3314 - Medical technology

Other members:

Carlos Gómez Peña
Jesús Poza Crespo
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María García Gadañon
Victor Martínez Cagigal
Félix del Campo Matías
Gonzalo Gutiérrez Tobal

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