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Description
Asymmetric synthesis of enantioselectively pure natural and non-natural nitrogenous derivatives. Synthesis of chiral catalysts derived from amino alcohols. Enantioselective supported catalysts. Study and development of fine chemistry synthetic methods applying homogeneous catalysis and organocatalysis. This way, from two complementary approaches, the complex problems posed by controlled preparation and modification of fragile molecules (usually chiral ones) are addressed. This research line studies and develops the chemical tools needed to obtain pure and pharmacologically active enantiomers. This technology can also be applied in the fragance and pesticide industries. We have developed methods for enantioselective supported catalysts preparation on synthetic (derived from polystyrene) or natural (chitin and chitin-based substances) polymers that are effective and easy-to-recover and studied its use in flow chemistryOther information
Number of researchers:
5
Development status:
In research and development phase
Differentiation in the market:
Novelty
Applicability of technology:
Yes
Companies and markets:
Fine chemistry and synthesis intermediate preparation industry, pharmaceutical industry, fragance industry, pesticide industry. Any industry related to High-Performance Liquid Chromatography (HPLC) and enantiomers separation.
Advantages:
Molecules' and catalysts' controlled design.
UNESCO Code:
2306 - Organic chemistry
Other members:
Celia Andrés Juan
José María Andrés García
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Alicia Maestro Fernández
Francisco Javier Nieto Román
Publicación seleccionada: Eur J. Org. Chem. 2017, 2683-2691. DOI: 10.1002/ejoc.201601640 See / Download resource |
Publicación seleccionada: Eur. J. Org. Chem. 2017, 3658-3665. DOI: 10.1002/ejoc.201700582 See / Download resource |
Publicación seleccionada: J. Org. Chem., 2017, 82 (16), pp 8444–8454. DOI: 10.1021/acs.joc.7b01177 See / Download resource |
Publicación seleccionada: Org. Lett., 2017, 19 (7), pp 1516–1519. DOI: 10.1021/acs.orglett.7b00252 See / Download resource |
The OBJECTIVES of the Asymmetric Synthesis group are:Study of symmetric synthesis processes of enantiomerically pure natural and unnatural nitrogen derivatives.Synthesis and application in enantioselective processes of chiral catalysts derived from a... Read more >
OBJECTIVESThe group dedicates its activity to the study of homogeneous catalysis for the synthesis of high added value molecules and special polymers with transition metal complexes. The main objectives are:Development of new catalytic processes with... Read more >
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