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CYTUVA

Organocatalysis and catalytic enantioselective processes

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Contact Information

Basic Information

  • UniversityUniversidad de Valladolid
  • Center
  • DepartmentOrganic Chemistry
  • Investigation GroupAsymmetric Synthesis


Description

Asymmetric synthesis of enantioselectively pure natural and non-natural nitrogenous derivatives. Synthesis of chiral catalysts derived from amino alcohols. Enantioselective supported catalysts. Study and development of fine chemistry synthetic methods applying homogeneous catalysis and organocatalysis. This way, from two complementary approaches, the complex problems posed by controlled preparation and modification of fragile molecules (usually chiral ones) are addressed. This research line studies and develops the chemical tools needed to obtain pure and pharmacologically active enantiomers. This technology can also be applied in the fragance and pesticide industries. We have developed methods for enantioselective supported catalysts preparation on synthetic (derived from polystyrene) or natural (chitin and chitin-based substances) polymers that are effective and easy-to-recover and studied its use in flow chemistry


Other information

Number of researchers:

5

Development status:

In research and development phase

Differentiation in the market:

Novelty

Applicability of technology:

Yes

Companies and markets:

Fine chemistry and synthesis intermediate preparation industry, pharmaceutical industry, fragance industry, pesticide industry. Any industry related to High-Performance Liquid Chromatography (HPLC) and enantiomers separation.

Advantages:

Molecules' and catalysts' controlled design.

UNESCO Code:

2306 - Organic chemistry

Other members:

Celia Andrés Juan
José María Andrés García
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Alicia Maestro Fernández
Francisco Javier Nieto Román

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Other resources

Publicación seleccionada: Eur J. Org. Chem. 2017, 2683-2691. DOI: 10.1002/ejoc.201601640
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Publicación seleccionada: Eur. J. Org. Chem. 2017, 3658-3665. DOI: 10.1002/ejoc.201700582
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Publicación seleccionada: J. Org. Chem., 2017, 82 (16), pp 8444–8454. DOI: 10.1021/acs.joc.7b01177
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Publicación seleccionada: Org. Lett., 2017, 19 (7), pp 1516–1519. DOI: 10.1021/acs.orglett.7b00252
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