Description

This research was born from one of the fundamental lines of research of the MIOMeT Research Group, which consists on the study of coordination complex with transition metals, mainly tricarbonyl, with the pyridine carboxaldehyde ligand. It is a protein marking methodology with metal complexes through amino groups that are included in the lysine peptidic chain. These complexes have tricarbonyl groups in their structure, which are sensitive to infrared (IR) detection. This is an important advantage regarding detection, since the necessary instruments to register IR spectrums are cheap, easy to use and it is a non-destructive technique. Besides, the expected signs appear on a very clean spetrum area for any biomolecule, so there is no risk of masking. Finally, it is possible to remove such marker with a simple procedure and without denaturalizing the protein.

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