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CYTUVA

GIR - Development and Teratology of the Central Nervous System and Sense Organs. Neurogenesis. Neuroregeneration.

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Contact Information

  • María Isabel Alonso Revuelta
  • Avda. Ramón y Cajal, 7
    Valladolid, Valladolid (47005)
  • Send email
  • 983186398
  • 983423022

Basic Information

  • UniversityUniversidad de Valladolid
  • Center
  • DepartmentPathological Anatomy, Microbiology, Preventive Medicine and Public Health, Forensic and Legal Medicine
  • Investigation GroupGIR - Development and Teratology of the Central Nervous System and Sense Organs. Neurogenesis. Neuroregeneration.


Description

OBJECTIVES
• Research group to study the mechanisms involved in neurogenesis and neuroregeneration.

The main objectives are:

- Identification of the mechanisms involved in the control of the replication and differentiation of neural stem cells during embryonic development.

- Application of embryonic control mechanisms to the replication and neuronal differentiation of stem cells from the adult central nervous system.

- Applicability of the mechanisms of control of neurogenesis in processes of neuronal regeneration. Study of its utility in the treatment of neurodegenerative diseases.

- Studies of mechanisms involved in the genesis of congenital malformations of the nervous system and sense organs.

- Involvement of extracellular matrix molecules in the genesis of congenital malformations.

RESEARCH LINES
• Study of the role of embryonal cerebrospinal fluid in the gene expression of neuroepithelial stem cells.
• Growth regulation factors and axonal myelination in the peripheral nervous system.
• Study of the role of embryonal cerebrospinal fluid in adult brain stem cells. Proteomic study of embryonal cerebrospinal fluid.
• Study of the role of embryonal cerebrospinal fluid in the replication and neurogenesis of neuroepithelial cells
• Study of extracellular matrix molecules in epithelial adhesion processes during development.


Other information

Number of researchers:

5

Technological Line(s):

- Health Sciences

Development status:

In research and development phase

Applicability of technology:

Yes

Other members:

Ángel Luis Gato Casado
Juan Francisco Arenillas Lara
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Estela Mª Carnicero Gila
Jose Mª Fidel Fernández Gato

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