Interdisciplinary center of the University of Valladolid dedicated to research on the safety and effects of drugs in human populations. cesme is part of the Recognized Research Group (GIR) on Pharmacogenetics, Cancer Genetics, Genetic Polymorphisms and Pharmacoepidemiology of the University of Valladolid. The ultimate goal of the Center is to contribute to improving the health of individuals through the most appropriate use of drugs.

cesme has its origin in the experience and work developed in the field of drug safety, since 1986, by the team of professors, researchers and technicians of the Pharmacovigilance Center of Castilla y León. The creation of cesme as a University Center was approved in 2010 by the University of Valladolid; previously it had been constituted as a University Institute (Instituto de Farmacoepidemiología - IFE). This status allows cesme to contract with public or private entities to carry out scientific or technical work and studies, as well as to give specialization courses.

The economic and social relevance of pharmacoepidemiology is considerable. It seeks to apply epidemiological knowledge, method and reasoning to the study of both the beneficial and adverse effects of drugs. In addition, pharmacoepidemiology is concerned with understanding how drugs are used.